50 Jahre Neubau Universitätsbibliothek Stuttgart 2011

T e i l 1 Impressum, Sponsoren - Seite 4 Stephan, Werner: Einleitung und Dank - Seite 9 Einfachheit in Form und Material - less is more: Klaus-Jürgen Zabel über den Bau der Universitätsbibliothek (Interview mit Ottmar Pertschi und Christiane Rambach) - Seite 13 Paulus, Stefan: Amerika als Vorbild? Anmerkungen zu den politischen und kulturhistorischen Bedingungen an (west)deutschen Universitäten in den 1950er Jahren - Seite 19 Hering, Jürgen: Max Kade und die Technische Hochschule Stuttgart - Seite 41 Becker, Norbert: Die Technische Hochschule Stuttgart und ihre Bibliothek in der Nachkriegszeit - Seite 63 T e i l 2 Rambach, Christiane: Eine Bibliothek sucht ihren Standort - Seite 75 T e i l 3 Rambach, Christiane: Architekten auf Reisen: "new standards in library design" in Stuttgart - Seite 97 T e i l 4 Philipp, Klaus Jan: Die Universitätsbibliothek im architekturgeschichtlichen Kontext - Seite 125 Huster-Braumann, Henriette: Maximilian Debus: die Universitätsbibliothek und ihre Schrift - Seite 145 T e i l 5 Jost, Holger; Stürzebecher, Jörg: Moderate Moderne: Innenraumgestaltung der Universitätsbibliothek Stuttgart - Seite 153 T e i l 6 Küster, Bärbel: Kunst und Konsens 1958 - 1962: zur Ankaufsgeschichte der Plastik von Hans Uhlmann für die Universitätsbibliothek Stuttgart - Seite 171 Szymczyk-Eggert, Elisabeth: Die Zweigbibliothek auf dem Campus in Stuttgart-Vaihingen: vom Provisorium zur Dauereinrichtung - Seite 191 T e i l 7 Stephan, Werner: Bibliotheken der Zukunft - Seite 221 T e i l 8 Anhang: Architekten der Universitätsbibliothek: Volkart, Zabel, Klauss und Koschlig (Christiane Rambach) - Seite 233 Richtfest am 31. Juli 1959 (Schwäbisches Stück zum Richtfest der THB am 31. Juli 1959 von Hans Volkart - Richtspruch des Zimmerpoliers der AG Kübler und Züblin zum Richtfest der Universitätsbibliothek am 31. Juli 1959) - Seite 237 "Es lebe die Bibliothek!" Interne Bibliothekseinweihung am 17. Februar 1962 - Seite 243 Skizzen (Gedanken zu einem Anbau an die Universitätsbibliothek Stuttgart von Klaus-Jürgen Zabel 2011 - Ihre Universitätsbibliothek zum Selberbauen von Stefan Pertschi) - Seite 247 Literatur zum Bau der Universitätsbibliothek Stuttgart (eine Auswahl - Christiane Rambach) - Seite 253 Abkürzungsverzeichnis, Abbildungsnachweise - Seite 258 Namen- und Sachregister (Ottmar Pertschi) - Seite 263 Autorenverzeichnis - S. 27

Year in review in Intensive Care Medicine, 2008: II. Experimental, acute respiratory failure and ARDS, mechanical ventilation and endotracheal intubation

SCOPUS: re.jinfo:eu-repo/semantics/publishe

Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study

BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.DESIGN, PATIENTS AND SETTING: This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries.MAIN OUTCOME MEASURES: Women and men were compared with respect to use of LTVV, defined as VT of 8 ml kg-1 or less predicted bodyweight (PBW). A VT was deemed 'default' if the set VT was a round number. A mediation analysis assessed which factors may explain the sex difference in use of LTVV during intra-operative ventilation.RESULTS: This analysis includes 9864 patients, of whom 5425 (55%) were women. A default VT was often set, both in women and men; mode VT was 500 ml. Median [IQR] VT was higher in women than in men (8.6 [7.7 to 9.6] vs. 7.6 [6.8 to 8.4] ml kg-1 PBW, P < 0.001). Compared with men, women were twice as likely not to receive LTVV [68.8 vs. 36.0%; relative risk ratio 2.1 (95% CI 1.9 to 2.1), P < 0.001]. In the mediation analysis, patients' height and actual body weight (ABW) explained 81 and 18% of the sex difference in use of LTVV, respectively; it was not explained by the use of a default VT.CONCLUSION: In this worldwide cohort of patients receiving intra-operative ventilation during general anaesthesia for surgery, women received a higher VT than men during intra-operative ventilation. The risk for a female not to receive LTVV during surgery was double that of males. Height and ABW were the two mediators of the sex difference in use of LTVV.TRIAL REGISTRATION: The study was registered at Clinicaltrials.gov, NCT01601223

Alpha-1 Antitrypsin Deficiency and Pulmonary Morbidity in Patients with Primary Immunodeficiency Disease: A Single-Center Experience

Background. Alpha-1 antitrypsin deficiency (AATD) is of importance in the pathogenesis of pulmonary emphysema, chronic obstructive pulmonary diseases (COPD), and bronchiectasis. Various pulmonary disorders are a typical feature of primary immunodeficiency disease (PID). This includes recurrent pulmonary infections, immunodysregulation, and autoinflammatory diseases. As a result, incidence of acute and chronic pulmonary diseases is higher. Interestingly, pulmonary morbidity in PID and AATD share similar features. To study the coexistence of AATD in patients suffering from PID, we performed the underlying investigation. Methods. We evaluated a study group of 149 patients (n = 149) with PID. In total, serum AAT concentrations were available for 110 patients (n = 110). For the identified patients, we analyzed both clinical associations and interactions. Results. Among the investigated patients, reduced serum AAT levels were detected in 7 patients. With regard to the genotype, PI∗ZZ was found in 2 patients, whereas PI∗MZ was observed in 5 patients. Independent of the underlying phenotype, obstructive lung diseases were found in 2 patients with PI∗ZZ and 2 patients with PI∗MZ. Conclusions. In Germany, the estimated percentage for PI∗ZZ and PI∗MZ is 0.01% and 1.9%, respectively. As demonstrated, the ratio in our study group was even higher. We identified seven patients with AATD. Since AATD contributes to pulmonary morbidity in PID patients, systematic underdiagnosis of the coexistence might yield a strong clinical impact. Hence, AAT analysis should be offered to all patients with confirmed PID diagnoses. To strengthen this finding, we suggest the investigation of larger databases

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial

International audienc